How two landmark studies are changing how we think.
Knowledge is Necessity. The key to recovery lies in knowing about how the inside of our head reacts to whatever is going on outside our head. This isn't esoteric academic knowledge. Our lives are at stake. We need to do our homework.
Scientific discovery holds out hope of effective and safe new treatments. More important, it is validating recovery techniques that we can apply right now. Please do not feel you have to comprehend every technical fine point. It is suggested, instead, you read for an appreciation for what is going on. The understanding will come in its own good time. In the meantime, treat this section as a good beach read and enjoy.
Knowledge is Necessity
Copyright 2008 John McManamy Contact
Dopamine - Serotonin's Secret Weapon
A smart dopamine med may do wonders for you. The problem is one doesn't exist.
Neurotransmitters are outside the cell. Let's open up the hood.
New studies are changing the way we think about our illness.
According to two studies, Nigeria is the happiest country with the lowest rates of menal illness. Huh?
Is there an adaptive advangtage to depression and bipolar?
"We have to show biologically what the gene does, what the mutation does, to cause the disease." - Raymond DePaulo MD
A Brain Primer
We know mental illness has to do with the brain, but do we know why?
Our Favorite Neurotransmitters
They already changed your life. Now find out why.
A Gene Primer
It's as easy as ATCG.
Epigenetics
A new science peels away another layer of the genetic onion.
Gene Quest
These days, we know better than to search for a depression gene or a bipolar gene.
The Cellular Bipolar Breakdown Lane
Is the mitochondria responsible?
Inhibiting GSK-3
A quirky little enzyme is about to hit the bigtime.
The World According to DARPP
A single molecule my be the brain's Rosetta Stone.
The Blood Brain Barrier
The blood brain barrier stands in the way of new drug development.
My Book
“The perfect book for those of us living with mood disorders.”
Sue Bergeson, president DBSA
Order nowStay Informed: McMan's Report
Mindfulness: The Ultimate Mood Stabilizer
The Buddha was on to something ...
Do people with bipolar cycle in and out of time? Call me bichronic.
Living Well with Depression and Bipolar Disorder
John McManamy discusses his book.
We tend to isolate. But isolation can bring on depression.
Depression and mania need not automatically follow when things start going wrong.